Chemicals & Small Molecules

Sorbicillin is a sorbic acid-like compound extracted from Penicillium, with anti-inflammatory and antibacterial activities. It induces apoptosis in HL-60 cells and has potential neuroprotective activity, making it useful for studying neurological diseases.

(S)-(+)-1,2-Propanediol ((2S)-propane-1,2-diol) is an endogenous compound produced by the engineered bacterium Lactococcus lactis.

1,1,3-Tribromoacetone (1,1,3-tribromo-2-propanone) is an impurity of methotrexate.

Budiodarone tartrate (ATI-2042 tartrate) is a chemical analog of Amiodarone, an antiarrhythmic drug that inhibits sodium, potassium, and calcium ion channels. It is used for studying atrial fibrillation.

Sarcosine oxidase (SAO) catalyzes the oxidative demethylation of sarcosine, producing glycine, H2O2, and 5,10-CH2-tetrahydrofolate, substances commonly utilized in biochemical reactions [1].

Creatinase (Creatine amidohydrolase), a hydrolase enzyme, catalyzes the conversion of creatine into sarcosine and urea. It is crucial for the enzymatic measurement of creatinine levels [1].

Cusatuzumab (ARGX-110) is a human CD70 monoclonal antibody with enhanced antibody-dependent cytotoxic activity that blocks CD70/CD27 signaling and targets CD70-expressing LSCs, eliminating LSCs in vitro and in xenograft assays.

Dacetuzumab (SGN 40) is a humanized anti-CD40 monoclonal antibody with antitumor activity that induces the expression of the pro-apoptotic proteins TAp63 and Fas, and can be used to study recurrent diffuse large B-cell lymphomas.

Margetuximab (MGAH-22) is a second generation anti-human epidermal growth factor receptor 2 protein (HER2) monoclonal antibody with anti-tumor activity for the study of metastatic HER2-positive breast cancer and for the synthesis of nanomedicines.