Labelling

Sulfo-Cy3 NHS ester is a fluorophore featuring a sulfonate group and an NHS functionality. NHS is a leaving group which can be easily displaced by amines to form amides while Cy3 is a cyanine dye with excitation and emission maxima at 555 nm and 570 nm respectively. The sulfonate group on the Cy3 dye increases this compound’s solubility in water.

Sulfo-Cy3 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy3 is a cyanine dye with excitation and emission maxima at 555 nm and 570 nm respectively. The sulfonate group on the Cy3 dye increases this compound’s water solubility.

Sulfo-Cy5 Picolyl Azide is a fluorophore featuring a sulfonate group and an azide. Azide groups are click chemistry handles which are reactive towards terminal alkynes and strained cyclooctynes such as BCN or DBCO. Cy5 is a cyanine dye with excitation and emission maxima at 651 nm and 670 nm respectively. The sulfonate group on the Cy5 dye increases this compound’s water solubility.

BP Fluor 350 Acid is an amine reactive, non-activated, water-soluble, blue-emitting dye used for derivatizing amine-containing molecules in the presence of activators (e.g. EDC or HATU) through a stable, covalent amide bond. The NHS ester (or succinimidyl ester) of this dye is also available for conjugating BP Fluor 350 to the primary amines of proteins or antibodies (Lys), amine-modified oligonucleotides, and other amine-containing molecules. BP Fluor 350 is a moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line routinely used for producing bright, blue fluorescent conjugates for imaging and flow cytometry. The emission of BP Fluor 350 conjugates is slightly shorter than that of AMCA or AMCA conjugates, reducing BP Fluor 350’s spectral overlap with the emission of fluorescein. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 350 Picolyl Azide is a blue-fluorescent azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 350 Azide is a blue-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctyne via a copper-free click chemistry reaction to form a stable triazole and does not require Cu-catalyst or elevated temperatures. BP Fluor 350 is a water-soluble, moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line. It is routinely used for generation of stable signal in imaging and flow cytometry. The brightness and photostability of blue dyes are best suited to direct imaging of high-abundance targets. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 350 Alkyne is a blue-fluorescent, alkyne-activated probe routinely used for imaging azide-tagged biomolecules. BP Fluor 350 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker. BP Fluor 350 is a water-soluble, moderately photostable, blue-fluorescent probe optimally excited by the 350 nm laser line. It is routinely used for generation of stable signal in imaging and flow cytometry. The brightness and photostability of blue dyes are best suited to direct imaging of high-abundance targets. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

BP Fluor 405 Acid is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. BP Fluor 405 conjugates are pH-insensitive from pH 4 to pH 10. The carboxylic acid of BP Fluor 405 is a reagent of choice for the preparation of custom activated esters that often are not commercially available. Examples of such activated esters include sulfo-NHS, TFP (2,3,5,6-Tetrafluorophenol), and STP (4-Sulfo-2,3,5,6-Tetrafluorophenol, Sodium Salt). Another common application for the non-activated carboxylic acid is peptide modification during solid phase synthesis, which usually requires in-situ activation with peptide coupling regents, e.g. HATU. BP Fluor 405 Acid is also often used for control experiments, and for calibration. Reagent grade, for research purpose. Please contact us for GMP-g

BP Fluor 405 Cadaverine is a carbonyl-reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Another common application for BP Fluor 405 Cadaverine is cell fixing by treatment with formaldehyde or glutaraldehyde. BP Fluor 405 is a water-soluble, blue-fluorescent dye that is often used in multi-color applications, including flow cytometry and super-resolution microscopy using STORM. Its excitation is ideally suited for the 407 nm spectral line of the krypton laser or the 408 nm violet laser diode. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.