Labelling

14:0 PEG PE, MW 2,000 is a PEG-modified phosphatidylethanolamine used in liposome creation of sterically stabilized liposomes with low reticuloendothelial system uptake and bolstered circulation duration to target cells.

BP Lipid 389 features a unique 2-hydroxyethyl piperazine head group with an ester linkage to two oleic fatty acid tails. This lipid may be used in the formulation of lipid nanoparticles drug delivery. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Our potent and selective hα1A adrenergic receptor fluorescent antagonist shows high affinity for α1A adrenergic receptor (Ki =28.3 nM measured in radioligand binding assay) and selectivity over α2A (Ki =1081 nM measured in radioligand binding assay). It is potentially suitable for fluorescence-based assays such as confocal microscopy or high content screening.

Our potent and selective hα1A adrenergic receptor fluorescent antagonist shows high affinity for alpha 1 adrenergic receptor (Ki =5 nM measured in radioligand binding assay) and selectivity over α2A (15% of displacement at 1 μM in radioligand binding assay). It is potentially suitable for fluorescence-based assays such as confocal microscopy, high content screening or fluorescence polarization.

Our CELT-145 ligand is a highly potent fluorescent antagonist developed for hA1R testing with a Ki of 160 nM in radioligand binding assay. The product comes in a 10ug vial that enables the preparation of 63ml of 100nM working solution to test AT1R. Our fluorescent antagonist is ideal for visualization in confocal microscopy and high-content system experiments. Our CELT-145 ligand is potentially suitable for other fluorescence-based assays such as HTRF.

Our potent CELT-150 VHL E3 ligase fluorescent ligand is a tracer for VHL E3 ligases binding assays, designed to perform affinity binding curves to VHL protein using TR-FRET homogenous technology. Von Hippel–Lindau protein (VHL) is the substrate recognition subunit of an E3 ligase recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a targeted protein.

Our hA3 Adenosine receptor fluorescent antagonist shows a high affinity and selectivity for A3 receptor over the other receptor subtypes (Ki =6.13 nM for A3 receptor in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.

Our hD2 Dopamine receptor fluorescent antagonist shows high affinity for hD2 receptor and selectivity over the other receptor subtypes (Ki =1.06 nM for hD2 receptor in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.

Our h5HT2B Serotonin receptor fluorescent ligand shows a high affinity for 5HT2B serotonin receptor and high selectivity over the other receptor subtypes (Ki =56.32 nM for 5HT2B receptor in radioligand binding assay).It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.