Results for Labelling ( 3759 )
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SPY555-FastAct_X is a bright, far red, fluorogenic & non toxic F-actin stain based on our SPY™ dyes series. SPY555-FastAct_X’s carefully optimized actin ligand allows to label Factin in live cells with very high specificity. SPY555-FastAct_X can label very fast actin dynamics but lacks undesired F-actin stabilization side effect. The probe does not require any genetic manipulation, transfection or overexpression of fluorescent proteins. SPY555-FastAct_X is based on a low phototoxicity, bright & highly photostable SPY555 fluorophore which is far superior than fluorescent proteins. SPY555-FastAct_X enables multicolor imaging with SPY505, SPY595, PY620, SPY650, SPY700, GFP or mcherry. SPY555-FastAct_X can be imaged with standard Cy3filterset. It can be used for widefield, confocal, SIM or STED imaging of living cells and tissue. Contains 1 vial of SPY555-FastAct_X (lyophilized)
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GolgiTrack™ Red is a cell-permeable, non-fixable, red-fluorescent dye that selectively stains Golgi apparatus in live cells. This dye has an excitation and emission maximum of 582/592 nm and can be efficiently excited using a TRITC filter. GolgiTrack™ Red can also be used in sphingolipid transport and metabolism studies. The GolgiTrack™ probes are also available in green color: GolgiTrack™ Green.
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Our potent hOT receptor fluorescent agonist shows high affinity for hOT receptor (Ki = 0.54 nM in radioligand binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy, high content system experiments and TR-FRET experiments. It is potentially suitable for other fluorescence-based assays.
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Our potent and selective hOT receptor fluorescent antagonist shows high affinity for hOT receptor (Kd = 1.59 nM in TR-FRET saturation binding assay). It allows to perform cell visualization in fluorescence microscopy, confocal microscopy, high content system experiments and TR-FRET experiments. It is potentially suitable for other fluorescence-based assays.
- From: £503.00
Our hD3 Dopamine receptor fluorescent ligandshows high affinity for hD2 receptor and partial selectivity over the other receptor subtypes (Ki =65.6 nM for hD3 receptor in radioligand binding assay). It has been validated in Fluorescence Polarization binding assays as a valid alternative to radioligand binding assays.It allows to perform cell visualization in fluorescence microscopy, confocal microscopy and high content system experiments. It is potentially suitable for other fluorescence-based assays.
- From: £232.00
Our red-emitting fluorescent GTPγS demonstrates outstanding performance in determining the functional activity of GPCR modulators in both agonist and antagonist modes. The assay requires only low concentrations (in the nM range) of CELT-503, enabling up to 20 plates of 96 wells to be processed using a single vial. The emission in the red spectrum minimizes autofluorescence effects and makes it highly suitable for multiplexing assay developments. CELT-503 addresses the limitations associated with the use of conventional [³⁵S]GTPγS, significantly broadening the range of assays in which it can be applied.